Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | DPEP1 | P16444 | 10/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717504 | 1.00 | CTSS (0.45) | CTSSCTSKDPEP1AAK1KMT2A | |
| SCHEMBL10717459 | 1.00 | CTSS (0.45) | CTSSCTSKDPEP1AAK1KMT2A | |
| SCHEMBL10716157 | 0.78 | CTSK (0.47) | CTSSCTSKAAK1KMT2AREN | |
| SCHEMBL10717435 | 0.72 | CTSK (0.44) | CTSSCTSKAAK1KMT2AREN | |
| SCHEMBL10715953 | 0.72 | CTSK (0.44) | CTSSCTSKAAK1KMT2AREN | |
| SCHEMBL12203697 | 0.71 | CTSK (0.59) | CTSSCTSKAAK1KMT2AREN | |
| SCHEMBL10718266 | 0.71 | CTSK (0.38) | CTSSCTSKAAK1KMT2AHDAC4 | |
| SCHEMBL7264559 | 0.70 | CTSK (0.53) | CTSSCTSKAAK1KMT2AREN | |
| SCHEMBL7264560 | 0.70 | CTSK (0.53) | CTSSCTSKAAK1KMT2AREN | |
| SCHEMBL6447508 | 0.69 | CTSK (0.54) | CTSSCTSKAAK1KMT2AREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | claimed |
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |