Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.77 |
| ▸ | RAB9A | P51151 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.77 |
| ▸ | HTT | P42858 | 3/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717626 | 1.00 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2HTTGAA | |
| SCHEMBL10717636 | 1.00 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2HTTGAA | |
| SCHEMBL2998577 | 0.87 | SMN1; SMN2 (1.00) | NPC1RAB9ASMN1; SMN2HTTGAA | |
| SCHEMBL10716420 | 0.85 | TGM2 (0.59) | NPC1RAB9ASMN1; SMN2HTTGAA | |
| SCHEMBL10716405 | 0.85 | TGM2 (0.59) | NPC1RAB9ASMN1; SMN2HTTGAA | |
| SCHEMBL10716411 | 0.85 | TGM2 (0.59) | NPC1RAB9ASMN1; SMN2HTTGAA | |
| SCHEMBL10718773 | 0.83 | NAPRT (0.55) | NPC1RAB9ASMN1; SMN2HTTGAA | |
| SCHEMBL10717676 | 0.83 | NAPRT (0.55) | NPC1RAB9ASMN1; SMN2HTTGAA | |
| SCHEMBL10717668 | 0.83 | NAPRT (0.55) | NPC1RAB9ASMN1; SMN2HTTGAA | |
| SCHEMBL10716302 | 0.81 | TGM2 (0.63) | NPC1RAB9ASMN1; SMN2HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H327-H | Nematicidal alkenanilides | FMC CORPORATION (US) | 1987-09-01 | — | — | US | disclosed |