Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717668 | 1.00 | NAPRT (0.55) | NAPRTHSD17B10TGM2DEGS1NPC1 | |
| SCHEMBL10717676 | 1.00 | NAPRT (0.55) | NAPRTHSD17B10TGM2DEGS1NPC1 | |
| SCHEMBL7679084 | 0.84 | SMN1; SMN2 (0.67) | NAPRTHSD17B10TGM2DEGS1NPC1 | |
| SCHEMBL396577 | 0.84 | SMN1; SMN2 (0.67) | NAPRTHSD17B10TGM2DEGS1NPC1 | |
| SCHEMBL10717636 | 0.83 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2GAAHTT | |
| SCHEMBL10716411 | 0.83 | TGM2 (0.59) | TGM2NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL10717626 | 0.83 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2GAAHTT | |
| SCHEMBL10716420 | 0.83 | TGM2 (0.59) | TGM2NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL10718651 | 0.83 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2GAAHTT | |
| SCHEMBL10716405 | 0.83 | TGM2 (0.59) | TGM2NPC1RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H327-H | Nematicidal alkenanilides | FMC CORPORATION (US) | 1987-09-01 | — | — | US | disclosed |
| US-4014679-A | HERBICIDES | ROUSSEL-UCLAF (FR) | 1977-03-29 | — | — | US | disclosed |