Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672665 | 0.89 | TNFRSF1A (0.52) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL9672672 | 0.89 | TNFRSF1A (0.52) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL5573107 | 0.85 | KDM4E (0.78) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL4644144 | 0.85 | KDM4E (0.78) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL9330303 | 0.84 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10PKM | |
| SCHEMBL9330299 | 0.84 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10PKM | |
| SCHEMBL2743832 | 0.82 | CYP1A2 (0.61) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL2743834 | 0.82 | CYP1A2 (0.61) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL25308221 | 0.82 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10HTR1A | |
| SCHEMBL9329870 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62175475-A | — | — | None | — | — | JP | disclosed |
| JP-S62175475-A | PIPERAZINE DERIVATIVE AND VASODILATOR CONTAINING SAID DERIVATIVE | TERUMO CORP | 1987-08-01 | — | — | JP | disclosed |