Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10720290 | 0.92 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL5056927 | 0.86 | ABCB1 (0.42) | ABCB1KCNK3KCNK9HPGDTDP1 | |
| SCHEMBL8772420 | 0.81 | ABCB1 (0.67) | ABCB1 | |
| SCHEMBL8383535 | 0.79 | ABCB1 (0.70) | ABCB1NPC1RAB9A | |
| SCHEMBL669093 | 0.78 | ABCB1 (0.51) | ABCB1NPC1RAB9A | |
| SCHEMBL20460223 | 0.76 | ABCB1 (0.51) | ABCB1 | |
| SCHEMBL10718578 | 0.74 | ABCB1 (0.45) | ABCB1HDAC6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL76595 | 0.74 | KCNK3 (0.50) | KCNK3KCNK9HDAC8HDAC6NPC1 | |
| SCHEMBL32672049 | 0.72 | ABCB1 (0.81) | ABCB1 | |
| SCHEMBL8461192 | 0.72 | ABCB1 (0.81) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |