Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2963689 | 0.86 | L3MBTL1 (0.53) | L3MBTL1KMT2APDE4BPDE4DUSP2 | |
| SCHEMBL30984176 | 0.85 | CA12 (0.43) | L3MBTL1KMT2APDE4BPDE4DUSP2 | |
| SCHEMBL10719138 | 0.83 | KMT2A (0.41) | KMT2APDE4BPDE4DUSP2MAPT | |
| SCHEMBL20027636 | 0.83 | KMT2A (0.41) | L3MBTL1KMT2APDE4BPDE4DUSP2 | |
| SCHEMBL20709979 | 0.83 | MAPT (0.46) | L3MBTL1KMT2APDE4BPDE4DMAPT | |
| SCHEMBL3382168 | 0.81 | KMT2A (0.44) | KMT2APDE4BPDE4DUSP2MAPT | |
| SCHEMBL1861023 | 0.81 | KMT2A (0.40) | L3MBTL1KMT2APDE4BPDE4DUSP2 | |
| SCHEMBL6270085 | 0.81 | KMT2A (0.40) | KMT2APDE4BPDE4DUSP2MAPT | |
| SCHEMBL8371895 | 0.80 | L3MBTL1 (0.45) | L3MBTL1KMT2ASMN1; SMN2CA12CA1 | |
| SCHEMBL10740359 | 0.80 | KMT2A (0.39) | L3MBTL1KMT2APDE4BPDE4DUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62004271-A | — | — | None | — | — | JP | disclosed |
| US-11339130-B1 | Calpain modulators and therapeutic uses thereof | BLADE THERAPEUTICS, INC. (US) | 2022-05-24 | — | — | US | disclosed |
| US-10934261-B2 | Calpain modulators and therapeutic uses thereof | BLADE THERAPEUTICS, INC. (US) | 2021-03-02 | — | — | US | disclosed |
| US-10894776-B2 | — | — | 2021-01-19 | — | — | US | disclosed |
| JP-S624271-A | PYRAZOLE DERIVATIVE AND PRODUCTION THEREOF | NISSAN CHEM IND LTD | 1987-01-10 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10934261-B2 | Calpain modulators and therapeutic uses thereof | CAPNS1, CAPN9, CAPN1 | L3MBTL1 3522/4885KMT2A 4418/4885PDE4B 1359/4885 |
| US-10894776-B2 | — | CAPNS1, CAPN9, CAPN2 | L3MBTL1 4453/4885KMT2A 4469/4885PDE4B 1176/4885 |
| US-11339130-B1 | Calpain modulators and therapeutic uses thereof | CAPNS1, CAPN9, CAPN1 | L3MBTL1 3522/4885KMT2A 4418/4885PDE4B 1359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.