Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 5/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722004 | 0.93 | HTR2A (0.53) | MEN1KMT2AHTR2ADRD2HTR7 | |
| Fumaric Acid SCHEMBL10718456 | 0.92 | HTR2A (0.46) | MEN1KMT2AHTR2APOLBDRD2 | |
| SCHEMBL10720179 | 0.88 | ALDH1A1 (0.56) | KMT2AHTR2APOLBDRD2ALDH1A1 | |
| Fumaric Acid SCHEMBL10718863 | 0.86 | HTR2A (0.49) | HTR2ADRD2HTR7HTR1ACCR3 | |
| Fumaric Acid SCHEMBL10718869 | 0.86 | HTR2A (0.49) | HTR2ADRD2HTR7HTR1ACCR3 | |
| Fumaric Acid SCHEMBL10719500 | 0.83 | ALDH1A1 (0.53) | KMT2AHTR2APOLBDRD2ALDH1A1 | |
| Maleic Acid SCHEMBL10719497 | 0.83 | ALDH1A1 (0.53) | KMT2AHTR2APOLBDRD2ALDH1A1 | |
| SCHEMBL24732017 | 0.82 | KMT2A (0.58) | MEN1KMT2AHTR2ADRD2ALDH1A1 | |
| SCHEMBL10461474 | 0.78 | PKM (0.63) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL27698523 | 0.76 | MEN1 (0.57) | MEN1KMT2APOLBALDH1A1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | claimed |