Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.54 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 3/20 | 0.49 |
| ▸ | NMBR | P28336 | 2/20 | 0.48 |
| ▸ | MME | P08473 | 3/20 | 0.47 |
| ▸ | ECE1 | P42892 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 4/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10725326 | 0.95 | REN (0.50) | RENHRH4CASP3CASP1NMBR | |
| SCHEMBL10639324 | 0.94 | REN (0.52) | RENHRH4CASP3CASP1NMBR | |
| SCHEMBL10636529 | 0.89 | REN (0.58) | RENCASP3NMBRCTSLCTSB | |
| SCHEMBL10981168 | 0.89 | REN (0.58) | RENCASP3NMBRCTSLCTSB | |
| SCHEMBL11015890 | 0.89 | REN (0.53) | RENCASP3CASP1NMBRMAPT | |
| SCHEMBL11014291 | 0.89 | REN (0.53) | RENCASP3CASP1NMBRMAPT | |
| SCHEMBL10633366 | 0.89 | REN (0.58) | RENCASP3NMBRCTSLCTSB | |
| SCHEMBL11015310 | 0.89 | REN (0.53) | RENCASP3CASP1NMBRMAPT | |
| SCHEMBL10976366 | 0.89 | REN (0.58) | RENCASP3NMBRCTSLCTSB | |
| SCHEMBL10443977 | 0.89 | CTSL (0.57) | MMEECE1CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698329-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-06 | — | — | US | disclosed |