Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14509577 | 0.91 | ESR1 (0.38) | ESR1ESR2MAPTADRA2AADRA2B | |
| SCHEMBL1797711 | 0.83 | KIF11 (0.52) | MAPTADRA2AADRA2BADRA2CLMNA | |
| Hydrochloric Acid SCHEMBL28869473 | 0.81 | KIF11 (0.50) | MAPTADRA2AADRA2BADRA2CLMNA | |
| Iodide SCHEMBL29229874 | 0.81 | KIF11 (0.50) | MAPTADRA2AADRA2BADRA2CLMNA | |
| Bromide SCHEMBL29203652 | 0.81 | KIF11 (0.50) | MAPTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL2080679 | 0.80 | NR1H3 (0.56) | SMN1; SMN2NR1H2NR1H3 | |
| SCHEMBL4597093 | 0.79 | HSD11B1 (0.44) | MAPTADRA2AADRA2BADRA2CSMN1; SMN2 | |
| SCHEMBL13884329 | 0.77 | ESR1 (0.46) | ESR1ESR2MAPTLMNAKIF11 | |
| SCHEMBL526383 | 0.76 | MAPT (0.58) | MAPTADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL13798571 | 0.76 | MAPT (0.40) | MAPTADRA2AADRA2BADRA2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0084269-B1 | RADIATION-SENSITIVE POLYIMIDE PRECURSOR COMPOSITION DERIVED FROM A DIARYL FLUORO COMPOUND | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-10-28 | — | — | EP | disclosed |
| US-4454220-A | WITH POLYFUNCTIONAL ACRYLIC COMPOUND AND INITIATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-12 | — | — | US | disclosed |
| US-4430418-A | AROMATIC POLYCARBOXYLIC COMPOUND, AND POLYFUNCTIONAL ACRYLATE COMPOUND WITH PROMOTER AND BIIMIDAZOLE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-02-07 | — | — | US | disclosed |
| US-4416973-A | Radiation-sensitive polyimide precursor composition derived from a diaryl fluoro compound | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-11-22 | — | — | US | disclosed |