Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.41 |
| ▸ | RELA | Q04206 | 7/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721576 | 1.00 | GAA (0.46) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL10802832 | 1.00 | GAA (0.46) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL10832796 | 0.79 | NAAA (0.49) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL10660414 | 0.79 | NAAA (0.49) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL17049788 | 0.79 | NAAA (0.49) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL10665432 | 0.79 | NAAA (0.49) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL10683017 | 0.79 | NAAA (0.49) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL10472944 | 0.79 | NAAA (0.49) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL11392394 | 0.77 | GAA (0.44) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL11392405 | 0.77 | GAA (0.44) | GAANFKB1NFKB2RELAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221954-A1 | CARBONATE SUBSTITUTED MONOBACTAMS AS ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1987-05-20 | — | — | EP | disclosed |
| EP-0076758-B1 | 4-ETHER DERIVATIVES OF 2-AZETIDINONE-1-SULFONIC ACIDS | E.R. Squibb & Sons, Inc. (US) | 1987-01-07 | — | — | EP | disclosed |
| WO-1986006722-A1 | CARBONATE SUBSTITUTED MONOBACTAMS AS ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1986-11-20 | — | — | WO | disclosed |
| EP-0076758-A2 | 4-Ether derivatives of 2-azetidinone-1-sulfonic acids | E.R. Squibb & Sons, Inc. (US) | 1983-04-13 | — | — | EP | disclosed |
| US-4257947-A | INTERMEDIATES FOR ANTIBACTERIAL CEPHALOSPORINS | SMITHKLINE CORPORATION (US) | 1981-03-24 | — | — | US | disclosed |
| US-4200572-A | Substituted azetidinones | SMITHKLINE CORPORATION (US) | 1980-04-29 | — | — | US | disclosed |
| US-4166816-A | CYCLIZATION | SMITHKLINE CORPORATION (US) | 1979-09-04 | — | — | US | disclosed |
| US-4103086-A | 8-Oxo-4-thia-1-azabicyclo (4.2.0)-oct-2-ene derivatives | SMITHKLINE CORPORATION (US) | 1978-07-25 | — | — | US | disclosed |
| US-4072674-A | FOR CEPHALOSPORIN CONGENERS | SMITHKLINE CORPORATION (US) | 1978-02-07 | — | — | US | disclosed |
| US-4000154-A | 3-Substituted-6β-(amino- and acylamino)-7-oxo-1,3-diazabicyclo[3.2.0]-h | SMITHKLINE CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |