Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679930 | 0.85 | LMNA (0.42) | AKR1C1HPGDLMNAHDAC4 | |
| SCHEMBL28139686 | 0.77 | AKR1C1 (0.42) | AKR1C1HPGDTSHRPOLBCYP3A4 | |
| SCHEMBL8529984 | 0.76 | AKR1C1 (0.45) | AKR1C1HPGDTSHRPOLBCYP3A4 | |
| SCHEMBL29155399 | 0.76 | AKR1C1 (0.45) | AKR1C1HPGDTSHRPOLBCYP3A4 | |
| SCHEMBL6695613 | 0.75 | HDAC4 (0.46) | AKR1C1HPGDTSHRLMNAHDAC4 | |
| SCHEMBL64920 | 0.75 | AKR1C1 (0.44) | AKR1C1TSHRPOLBCYP3A4PARP1 | |
| SCHEMBL28231289 | 0.75 | HDAC4 (0.46) | AKR1C1HPGDTSHRLMNAHDAC4 | |
| Benzene SCHEMBL29067363 | 0.75 | HDAC4 (0.46) | AKR1C1HPGDTSHRLMNAHDAC4 | |
| SCHEMBL27279 | 0.75 | HDAC4 (0.46) | AKR1C1HPGDTSHRLMNAHDAC4 | |
| SCHEMBL4266410 | 0.74 | ALDH1A1 (0.44) | AKR1C1HPGDTSHRPOLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |