Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10461055 | 0.95 | KCNH2 (0.59) | KCNH2MEN1HRH3PAX8CYP2J2 | |
| SCHEMBL10461861 | 0.92 | KCNH2 (0.70) | KCNH2MEN1HRH3PAX8KMT2A | |
| SCHEMBL10460724 | 0.91 | KCNH2 (0.64) | KCNH2MEN1HRH3PAX8KMT2A | |
| SCHEMBL10461340 | 0.89 | KCNH2 (0.64) | KCNH2MEN1HRH3PAX8CYP2J2 | |
| SCHEMBL10459164 | 0.89 | KCNH2 (0.64) | KCNH2MEN1HRH3PAX8CYP2J2 | |
| SCHEMBL10460419 | 0.89 | KCNH2 (0.64) | KCNH2MEN1HRH3PAX8CYP2J2 | |
| SCHEMBL10461657 | 0.87 | KCNH2 (0.61) | KCNH2MEN1HRH3PAX8KMT2A | |
| SCHEMBL10460508 | 0.87 | KCNH2 (0.64) | KCNH2MEN1HRH3PAX8KMT2A | |
| SCHEMBL10461280 | 0.87 | HTR1A (0.66) | KCNH2MEN1HRH3PAX8KMT2A | |
| SCHEMBL10460949 | 0.86 | KCNH2 (0.73) | KCNH2MEN1PAX8KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | claimed |