Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | DRD5 | P21918 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10461861 | 0.94 | KCNH2 (0.70) | KCNH2MEN1PAX8HTR2AHRH3 | |
| SCHEMBL10722742 | 0.91 | KCNH2 (0.61) | KCNH2MEN1PAX8HTR2AHRH3 | |
| SCHEMBL10461340 | 0.91 | KCNH2 (0.64) | KCNH2MEN1PAX8HTR2AHRH3 | |
| SCHEMBL10460419 | 0.91 | KCNH2 (0.64) | KCNH2MEN1PAX8HTR2AHRH3 | |
| SCHEMBL10459164 | 0.91 | KCNH2 (0.64) | KCNH2MEN1PAX8HRH3KMT2A | |
| SCHEMBL10461657 | 0.89 | KCNH2 (0.61) | KCNH2MEN1PAX8HTR2AHRH3 | |
| SCHEMBL10460508 | 0.89 | KCNH2 (0.64) | KCNH2MEN1PAX8HTR2AHRH3 | |
| SCHEMBL10461280 | 0.89 | HTR1A (0.66) | KCNH2MEN1PAX8HTR2AHRH3 | |
| SCHEMBL10460949 | 0.88 | KCNH2 (0.73) | KCNH2MEN1PAX8HTR2AKMT2A | |
| SCHEMBL10558087 | 0.88 | KCNH2 (0.60) | KCNH2MEN1PAX8HTR2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4950674-A | Arylalkylheterocyclic amines,N-substituted by aryloxyalkyl group in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1990-08-21 | — | — | US | disclosed |