Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722850 | 1.00 | REN (0.69) | REN | |
| SCHEMBL10722916 | 0.94 | REN (0.62) | REN | |
| SCHEMBL10722928 | 0.94 | REN (0.62) | REN | |
| SCHEMBL10724716 | 0.93 | REN (0.60) | REN | |
| SCHEMBL11013004 | 0.93 | REN (0.60) | REN | |
| SCHEMBL10724720 | 0.93 | REN (0.60) | REN | |
| SCHEMBL10722781 | 0.92 | REN (0.59) | REN | |
| SCHEMBL10722786 | 0.92 | REN (0.59) | REN | |
| SCHEMBL10722612 | 0.92 | REN (0.58) | REN | |
| SCHEMBL10722618 | 0.92 | REN (0.58) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698329-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-06 | — | — | US | claimed |
| US-4698329-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0152255-A2 | New renin-inhibitory peptides and their use | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |