SCHEMBL10722916

SCHEMBL10722916

CCC(C)CNC(=O)CC(O)C(CC(C)C)NC(=O)[C@H](Cc1cscn1)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)OCc1ccc(OC)cc1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10722928 1.00 REN (0.62) REN
SCHEMBL10722850 0.94 REN (0.69) REN
SCHEMBL10722862 0.94 REN (0.69) REN
SCHEMBL10725368 0.91 REN (0.68) REN
SCHEMBL10725357 0.91 REN (0.68) REN
SCHEMBL10720537 0.90 REN (0.50) REN
SCHEMBL10720527 0.90 REN (0.50) REN
SCHEMBL10721087 0.90 REN (0.63) REN
SCHEMBL10721096 0.90 REN (0.63) REN
SCHEMBL10720777 0.88 REN (0.57) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4698329-A HYPOTENSIVE AGENTS SANKYO COMPANY, LIMITED (JP) 1987-10-06 — — US disclosed
EP-0152255-A2 New renin-inhibitory peptides and their use SANKYO COMPANY LIMITED (JP) 1985-08-21 — — EP disclosed
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