Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12807818 | 0.88 | LMNA (0.81) | KMT2ALMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL29819356 | 0.87 | KCNH2 (0.81) | KMT2ALMNAKDM4EALDH1A1HSD17B10 | |
| Laudanosine SCHEMBL29822950 | 0.83 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Laudanosine SCHEMBL30816021 | 0.83 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Laudanosine SCHEMBL466528 | 0.83 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Laudanosine SCHEMBL466529 | 0.83 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Laudanosine SCHEMBL6130845 | 0.83 | LMNA (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 | |
| Dimethylgrisabine SCHEMBL30735570 | 0.83 | LMNA (0.84) | KMT2ALMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL21095124 | 0.83 | LMNA (0.75) | KMT2ALMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL1389166 | 0.82 | KDM4E (1.00) | LMNAKDM4EALDH1A1HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62242667-A | — | — | None | — | — | JP | disclosed |
| JP-S62242667-A | BENZYLISOQUINOLINE DERIVATIVE | KAKEN SHIYOUYAKU KK | 1987-10-23 | — | — | JP | disclosed |