Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10723855 | 1.00 | CNR2 (0.47) | CNR2KCNK3ALDH1A1THRBBLM | |
| SCHEMBL10723247 | 1.00 | CNR2 (0.47) | CNR2KCNK3ALDH1A1THRBBLM | |
| SCHEMBL10723317 | 0.91 | DEGS1 (0.44) | CNR2KCNK3ALDH1A1THRBBLM | |
| SCHEMBL10723306 | 0.91 | DEGS1 (0.44) | CNR2KCNK3ALDH1A1THRBBLM | |
| SCHEMBL10728359 | 0.90 | FAAH (0.53) | FAAHAPLNRSMN1; SMN2SLC6A5LPAR3 | |
| SCHEMBL10728366 | 0.90 | FAAH (0.53) | FAAHAPLNRSMN1; SMN2SLC6A5LPAR3 | |
| SCHEMBL10728822 | 0.90 | FAAH (0.53) | FAAHAPLNRSMN1; SMN2SLC6A5LPAR3 | |
| SCHEMBL10726064 | 0.89 | FAAH (0.43) | CNR2FAAHAPLNRSMN1; SMN2SLC6A5 | |
| SCHEMBL10723217 | 0.89 | FAAH (0.43) | CNR2FAAHAPLNRSMN1; SMN2SLC6A5 | |
| SCHEMBL10723233 | 0.89 | FAAH (0.43) | CNR2FAAHAPLNRSMN1; SMN2SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665053-A | HYDROPHOBIC CARBOXYLIC MODIFIER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1987-05-12 | — | — | US | claimed |
| EP-0126009-B1 | PEPTIDE DERIVATIVES, THEIR PREPARATION AND USE AS ELASTASE INHIBITORS | Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1987-01-14 | — | — | EP | claimed |
| US-4665053-A | HYDROPHOBIC CARBOXYLIC MODIFIER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1987-05-12 | — | — | US | disclosed |
| EP-0126009-B1 | PEPTIDE DERIVATIVES, THEIR PREPARATION AND USE AS ELASTASE INHIBITORS | Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1987-01-14 | — | — | EP | disclosed |
| EP-0126009-A1 | Peptide derivatives, their preparation and use as elastase inhibitors | Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1984-11-21 | — | — | EP | disclosed |