Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 4/20 | 0.79 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MMP14 | P50281 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | MPL | P40238 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394555 | 0.88 | GLO1 (0.68) | GLO1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL10724086 | 0.88 | GLO1 (0.82) | GLO1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL10724094 | 0.88 | GLO1 (0.82) | GLO1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL10723387 | 0.87 | GLO1 (0.80) | GLO1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL10723402 | 0.87 | GLO1 (0.80) | GLO1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL29421893 | 0.86 | GLO1 (0.64) | GLO1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL12960416 | 0.82 | GLO1 (0.72) | GLO1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL29624560 | 0.81 | THRB (0.61) | GLO1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL8947444 | 0.81 | GLO1 (0.71) | GLO1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL136632 | 0.81 | THRB (0.64) | GLO1MAPTKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62250072-A | — | — | None | — | — | JP | disclosed |
| JP-S62250072-A | NOVEL AZO LAKE PIGMENT, PRODUCTION THEREOF AND PRINTING INK CONTAINING SAME | TOYO INK MFG CO LTD | 1987-10-30 | — | — | JP | disclosed |