Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721842 | 0.88 | KDM4E (0.42) | KDM4ENPSR1DRD2LMNAHTR2A | |
| SCHEMBL28339029 | 0.86 | DRD2 (0.52) | KDM4ENPSR1DRD2LMNAHTR2A | |
| SCHEMBL10723753 | 0.85 | KDM4E (0.61) | KDM4ENPSR1DRD2LMNAHTR2A | |
| SCHEMBL10671426 | 0.83 | KDM4E (0.51) | KDM4ENPSR1LMNATSHRCYP3A4 | |
| SCHEMBL10560818 | 0.83 | NPSR1 (0.51) | KDM4ENPSR1LMNACYP3A4KMT2A | |
| SCHEMBL12515330 | 0.78 | CYP3A4 (0.52) | KDM4ENPSR1TSHRCYP3A4KMT2A | |
| SCHEMBL3651991 | 0.77 | CYP3A4 (0.61) | KDM4ETSHRMAPK1CYP3A4KMT2A | |
| SCHEMBL8902778 | 0.76 | CYP3A4 (0.54) | KDM4ELMNATSHRCYP3A4KMT2A | |
| SCHEMBL10723820 | 0.76 | DRD2 (0.50) | DRD2LMNAHTR2BADRA2ATSHR | |
| SCHEMBL10740489 | 0.76 | TRPV4 (0.51) | KDM4EHTR2AHTR2BTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673686-A | CNS MODIFIERS, ANTI-APOMORPHINE ANTIENETIC ACITIVTY/ | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLE DE L'ILE DE FRANCE (FR) | 1987-06-16 | — | — | US | disclosed |