Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.65 |
| ▸ | DRD3 | P35462 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.51 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.51 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | FPR3 | P25089 | 1/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19849351 | 0.92 | SMN1; SMN2 (0.70) | DRD2DRD3SMN1; SMN2ADRA1ANAAA | |
| SCHEMBL14761832 | 0.88 | DRD2 (0.57) | DRD2DRD3SMN1; SMN2ADRA1ANAAA | |
| SCHEMBL10723369 | 0.88 | SMN1; SMN2 (0.55) | DRD2DRD3SMN1; SMN2ADRA1ANAAA | |
| SCHEMBL10721902 | 0.88 | NAAA (0.58) | DRD2DRD3SMN1; SMN2ADRA1ANAAA | |
| SCHEMBL13875530 | 0.87 | SMN1; SMN2 (0.72) | DRD2DRD3SMN1; SMN2NAAAMEN1 | |
| SCHEMBL26844232 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14761461 | 0.86 | SMN1; SMN2 (0.56) | DRD2DRD3SMN1; SMN2ADRA1ANAAA | |
| SCHEMBL14761718 | 0.83 | DRD3 (0.71) | DRD2DRD3SMN1; SMN2ADRA1AMEN1 | |
| SCHEMBL7385554 | 0.83 | DRD2 (0.55) | DRD2DRD3SMN1; SMN2ADRA1ANAAA | |
| SCHEMBL17172545 | 0.82 | NAAA (0.82) | DRD2DRD3SMN1; SMN2NAAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665410-A | THERMOGRAPHY | RICOH COMPANY, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| US-4663641-A | LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES | RICOH COMPANY, LTD. (JP) | 1987-05-05 | — | — | US | disclosed |