Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.70 |
| ▸ | DRD2 | P14416 | 3/20 | 0.66 |
| ▸ | HTR2A | P28223 | 3/20 | 0.66 |
| ▸ | HRH2 | P25021 | 1/20 | 0.65 |
| ▸ | HRH1 | P35367 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.59 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10724043 | 1.00 | SIGMAR1 (0.70) | SIGMAR1DRD2HTR2AHRH2HRH1 | |
| SCHEMBL10722011 | 1.00 | SIGMAR1 (0.70) | SIGMAR1DRD2HTR2AHRH2HRH1 | |
| SCHEMBL16980657 | 0.98 | SIGMAR1 (0.72) | SIGMAR1DRD2HTR2AHRH2HRH1 | |
| SCHEMBL10722663 | 0.94 | DRD2 (0.69) | SIGMAR1DRD2HTR2AHRH2HRH1 | |
| SCHEMBL10727700 | 0.88 | KMT2A (0.69) | SIGMAR1DRD2HTR2AHRH2HRH1 | |
| SCHEMBL18770805 | 0.88 | DRD2 (0.82) | SIGMAR1DRD2HTR2AKCNH2MEN1 | |
| Benzamide SCHEMBL10721865 | 0.87 | DRD2 (0.61) | SIGMAR1DRD2HTR2AHRH2HRH1 | |
| Octadecanoic Acid Amide SCHEMBL10727354 | 0.87 | HRH2 (0.61) | SIGMAR1DRD2HTR2AHRH2HRH1 | |
| SCHEMBL10726931 | 0.87 | HRH2 (0.61) | SIGMAR1DRD2HTR2AHRH2HRH1 | |
| SCHEMBL10727351 | 0.86 | HRH2 (0.61) | SIGMAR1DRD2HTR2AHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663641-A | LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES | RICOH COMPANY, LTD. (JP) | 1987-05-05 | — | — | US | disclosed |