Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10724198 | 0.86 | TMEM97 (0.41) | TMEM97NPY5RSIGMAR1 | |
| Hydrochloric Acid SCHEMBL10721606 | 0.85 | TMEM97 (0.40) | TMEM97NPY5RSIGMAR1 | |
| SCHEMBL10656985 | 0.84 | TMEM97 (0.40) | TMEM97NPY5R | |
| SCHEMBL10720127 | 0.84 | TMEM97 (0.40) | TMEM97NPY5RSIGMAR1 | |
| Hydrochloric Acid SCHEMBL10723941 | 0.83 | TMEM97 (0.39) | TMEM97NPY5RSIGMAR1 | |
| Hydrochloric Acid SCHEMBL10721852 | 0.82 | TMEM97 (0.38) | TMEM97NPY5RSIGMAR1 | |
| SCHEMBL10723450 | 0.81 | HRH4 (0.35) | CYP2D6CYP19A1HTT | |
| SCHEMBL10974768 | 0.81 | TMEM97 (0.47) | TMEM97CYP2D6USP2HTR2AHTR2C | |
| SCHEMBL8894960 | 0.80 | TMEM97 (0.49) | TMEM97CYP2D6SIGMAR1TP53CYP3A4 | |
| SCHEMBL10724235 | 0.79 | TMEM97 (0.36) | TMEM97NPY5RSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232740-A1 | N-containing fused heterocyclic compounds, processes for the preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-19 | — | — | EP | disclosed |