Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10974768 | 0.88 | TMEM97 (0.47) | TMEM97DRD2DRD4CYP3A4CYP2D6 | |
| SCHEMBL11403161 | 0.86 | TMEM97 (0.45) | TMEM97DRD2DRD4SIGMAR1MAPK1 | |
| SCHEMBL8902245 | 0.84 | TMEM97 (0.47) | TMEM97DRD2DRD4SIGMAR1HTR1A | |
| SCHEMBL10724198 | 0.82 | TMEM97 (0.41) | TMEM97DRD2DRD4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10721606 | 0.81 | TMEM97 (0.40) | TMEM97SIGMAR1 | |
| SCHEMBL10720127 | 0.81 | TMEM97 (0.40) | TMEM97SIGMAR1 | |
| SCHEMBL10724191 | 0.80 | TMEM97 (0.41) | TMEM97CYP3A4CYP2D6SIGMAR1TP53 | |
| Hydrochloric Acid SCHEMBL10723941 | 0.80 | TMEM97 (0.39) | TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10721852 | 0.79 | TMEM97 (0.38) | TMEM97SIGMAR1 | |
| SCHEMBL10656985 | 0.78 | TMEM97 (0.40) | TMEM97PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043282-A2 | BENZOTHIAZOLINONES AS ANTI-ASTHMATIC AGENTS | KLINGE PHARMA GMBH (DE) | 1997-11-20 | — | — | WO | disclosed |