Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894960 | 0.88 | TMEM97 (0.49) | TMEM97DRD2DRD4SIGMAR1HTR1A | |
| SCHEMBL11403161 | 0.87 | TMEM97 (0.45) | TMEM97DRD2DRD4SIGMAR1HTR1A | |
| SCHEMBL8902245 | 0.85 | TMEM97 (0.47) | TMEM97DRD2DRD4SIGMAR1HTR1A | |
| SCHEMBL11442653 | 0.83 | SIGMAR1 (0.34) | TMEM97SIGMAR1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10483050 | 0.83 | TMEM97 (0.32) | TMEM97CYP2D6LMNAALDH1A1HPGD | |
| SCHEMBL10724198 | 0.83 | TMEM97 (0.41) | TMEM97DRD2DRD4SIGMAR1NPY5R | |
| Hydrochloric Acid SCHEMBL10721606 | 0.82 | TMEM97 (0.40) | TMEM97SIGMAR1NPY5R | |
| SCHEMBL10656985 | 0.81 | TMEM97 (0.40) | TMEM97NPY5R | |
| SCHEMBL10720127 | 0.81 | TMEM97 (0.40) | TMEM97SIGMAR1NPY5R | |
| SCHEMBL10724191 | 0.81 | TMEM97 (0.41) | TMEM97SIGMAR1HTR1AHTR7NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58052281-A | — | — | None | — | — | JP | disclosed |
| JP-57165381-A | — | — | None | — | — | JP | disclosed |
| JP-57118576-A | — | — | None | — | — | JP | disclosed |
| JP-60228468-A | — | — | None | — | — | JP | disclosed |
| JP-56020582-A | — | — | None | — | — | JP | disclosed |
| JP-55100373-A | — | — | None | — | — | JP | disclosed |
| JP-55000345-A | — | — | None | — | — | JP | disclosed |
| JP-S60228468-A | 1,2-BIS(2-OXO-3-BENZOTHIAZOLINYL)ETHANONE AND PREPARATION THEREOF | ARAKAWA CHIYOUTAROU KK | 1985-11-13 | — | — | JP | disclosed |
| JP-S5852281-A | BENZOTHIAZOLINONE DERIVATIVE AND ITS PREPARATION | SHIONO KORYO KK | 1983-03-28 | — | — | JP | disclosed |
| JP-S57165381-A | NOVEL PIPERAZING DERIVATIVE AND ITS PREPARATION | KANO SHINZO | 1982-10-12 | — | — | JP | disclosed |
| JP-S57118576-A | PREPARATION OF 5-CHLORO-3-(4-(2-HYDROXYETHYL)-1- PIPERAZINYL)-CARBONYLMETHYL-2-BENZOTHIAZOLINONE OR SALT THEREOF | HAMARI YAKUHIN KOGYO KK | 1982-07-23 | — | — | JP | disclosed |
| JP-S5620582-A | NOVEL 2-BENZOTHIAZOLINONE DERIVATIVE AND ITS PREPARATION | HAMARI YAKUHIN KOGYO KK | 1981-02-26 | — | — | JP | disclosed |
| JP-S55100373-A | PREPARATION OF ACID AMIDE | SHIONO KORYO KK | 1980-07-31 | — | — | JP | disclosed |
| JP-S55345-A | 2-IMINOBENZTHIAZOLINE DERIVATIVE | IWAKI SEIYAKU KK | 1980-01-05 | — | — | JP | disclosed |