Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | AHR | P35869 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928844 | 0.89 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1NPC1MAPT | |
| SCHEMBL10722950 | 0.85 | NPC1 (0.64) | KMT2AMEN1ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL10320585 | 0.83 | ALDH1A1 (0.68) | KMT2AMEN1ALDH1A1NPC1MAPT | |
| SCHEMBL10506338 | 0.83 | NPC1 (0.62) | KMT2AALDH1A1NPC1GAASMN1; SMN2 | |
| SCHEMBL10504806 | 0.82 | KMT2A (0.72) | KMT2AMEN1ALDH1A1NPC1MAPT | |
| SCHEMBL10505347 | 0.82 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1NPC1MAPT | |
| SCHEMBL1193504 | 0.81 | NPC1 (0.65) | KMT2AMEN1ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL15988631 | 0.80 | ALDH1A1 (0.68) | KMT2AMEN1ALDH1A1NPC1MAPT | |
| SCHEMBL11336785 | 0.79 | POLB (0.61) | ALDH1A1NPC1GAASMN1; SMN2KDM4E | |
| SCHEMBL28972912 | 0.78 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4642313-A | ANTILIPEMIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1987-02-10 | — | — | US | disclosed |
| EP-0087782-B1 | FURYLOXAZOLYLACETIC ACID DERIVATIVES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1986-05-21 | — | — | EP | disclosed |
| EP-0087782-A1 | Furyloxazolylacetic acid derivatives, process for preparing same and pharmaceutical compositions containing same | Tanabe Seiyaku Co., Ltd. (JP) | 1983-09-07 | — | — | EP | disclosed |