Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | AHR | P35869 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10724596 | 0.89 | KMT2A (0.62) | ALDH1A1KMT2AMEN1NPC1MAPT | |
| SCHEMBL28928860 | 0.87 | RAB9A (0.55) | ALDH1A1KMT2AMEN1NPC1MAPT | |
| SCHEMBL10320585 | 0.83 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1NPC1MAPT | |
| SCHEMBL23014488 | 0.83 | ALDH1A1 (0.74) | ALDH1A1KMT2ANPC1GAASMN1; SMN2 | |
| SCHEMBL28928853 | 0.82 | KMT2A (0.72) | ALDH1A1KMT2ANPC1MAPTGAA | |
| SCHEMBL28928816 | 0.82 | KMT2A (0.64) | ALDH1A1KMT2AMEN1NPC1MAPT | |
| SCHEMBL23014296 | 0.82 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1NPC1MAPT | |
| SCHEMBL26644596 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KMT2AMEN1NPC1HPGD | |
| SCHEMBL23014152 | 0.81 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1NPC1MAPT | |
| SCHEMBL1193504 | 0.81 | NPC1 (0.65) | ALDH1A1KMT2AMEN1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |