Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5744084 | 0.73 | DPP4 (0.50) | MAPTGAAALDH1A1KDM4EPOLB | |
| SCHEMBL6366424 | 0.73 | LMNA (0.54) | L3MBTL1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL3890306 | 0.70 | SMN1; SMN2 (0.52) | L3MBTL1MAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL10724543 | 0.70 | L3MBTL1 (0.53) | L3MBTL1MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL12072042 | 0.70 | KDM4E (0.42) | MTNR1AMTNR1BL3MBTL1MAPTGAA | |
| SCHEMBL7370093 | 0.69 | GRM6 (0.39) | MTNR1AMTNR1BALDH1A1KDM4EPOLB | |
| SCHEMBL5242387 | 0.69 | MAPT (0.53) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL31063213 | 0.69 | DPP4 (0.46) | MTNR1AMTNR1BALDH1A1KDM4EHSD17B10 | |
| SCHEMBL490608 | 0.69 | CYP4F2 (0.51) | L3MBTL1GAAALDH1A1KDM4EPOLB | |
| SCHEMBL30011105 | 0.69 | DPP4 (0.46) | MTNR1AMTNR1BGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067105-B1 | ALLYL AMINE MAO INHIBITORS | MERRELL DOW FRANCE ET CIE (FR) | 1987-09-23 | — | — | EP | disclosed |
| EP-0067105-A2 | Allyl amine MAO inhibitors | MERRELL DOW FRANCE ET CIE (FR) | 1982-12-15 | — | — | EP | disclosed |