Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721842 | 0.88 | KDM4E (0.42) | KDM4ENPSR1ALDH1A1CA12CA1 | |
| SCHEMBL10723753 | 0.86 | KDM4E (0.61) | KDM4ENPSR1ALDH1A1HPGDLCK | |
| SCHEMBL8576478 | 0.84 | KDM4E (0.52) | KDM4ENPSR1ALDH1A1CISD1HPGD | |
| SCHEMBL10721874 | 0.84 | KDM4E (0.52) | KDM4ENPSR1ALDH1A1CISD1HPGD | |
| SCHEMBL7441007 | 0.83 | LCK (0.56) | KDM4ENPSR1ALDH1A1HPGDCA12 | |
| SCHEMBL14871094 | 0.83 | KDM4E (0.51) | KDM4ENPSR1ALDH1A1HPGDLCK | |
| SCHEMBL28899597 | 0.83 | CISD1 (0.66) | KDM4ENPSR1CISD1CA12CA1 | |
| SCHEMBL11817254 | 0.82 | CISD1 (0.64) | ALDH1A1CISD1CA12CA1CA2 | |
| SCHEMBL3313702 | 0.82 | ADRA2A (0.53) | KDM4ENPSR1ALDH1A1HPGDCA12 | |
| SCHEMBL31705095 | 0.82 | KDM4E (0.50) | KDM4ENPSR1ALDH1A1CISD1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673686-A | CNS MODIFIERS, ANTI-APOMORPHINE ANTIENETIC ACITIVTY/ | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLE DE L'ILE DE FRANCE (FR) | 1987-06-16 | — | — | US | disclosed |