SCHEMBL3313702

SCHEMBL3313702

CCS(=O)(=O)c1cc(C(=O)O)c(OC)cc1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADRA2A P08913 2/20 0.53
▸ DRD3 P35462 2/20 0.53
▸ TSHR P16473 2/20 0.53
▸ LMNA P02545 1/20 0.53
▸ DRD2 P14416 1/20 0.53
▸ ALOX15 P16050 1/20 0.53
▸ ADRA2B P18089 1/20 0.53
▸ ADRA2C P18825 1/20 0.53
▸ HTR2A P28223 1/20 0.53
▸ MAPK1 P28482 1/20 0.53
▸ HTR7 P34969 1/20 0.53
▸ HRH1 P35367 1/20 0.53
▸ HTR2B P41595 1/20 0.53
▸ KCNH2 Q12809 1/20 0.53
▸ HRH3 Q9Y5N1 1/20 0.53
▸ KDM4E B2RXH2 5/20 0.50
▸ NPSR1 Q6W5P4 1/20 0.50
▸ ALDH1A1 P00352 3/20 0.47
▸ HPGD P15428 2/20 0.44
▸ LCK P06239 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29510768 1.00 ADRA2A (0.53) ADRA2ADRD3TSHRLMNADRD2
Water SCHEMBL7373734 0.98 ADRA2A (0.52) ADRA2ADRD3TSHRLMNADRD2
Ethylene Glycol SCHEMBL29225457 0.96 ADRA2A (0.50) ADRA2ADRD3TSHRLMNADRD2
SCHEMBL7377119 0.90 KDM4E (0.47) ADRA2ADRD3TSHRLMNADRD2
SCHEMBL13395713 0.90 TSHR (0.47) ADRA2ADRD3TSHRLMNADRD2
SCHEMBL24694102 0.88 DRD2 (0.53) ADRA2ADRD3TSHRLMNADRD2
SCHEMBL28430952 0.88 LMNA (0.52) ADRA2ADRD3TSHRLMNADRD2
SCHEMBL12070949 0.87 GAA (0.57) ADRA2ADRD3TSHRLMNADRD2
SCHEMBL31376269 0.87 GAA (0.57) ADRA2ADRD3TSHRLMNADRD2
SCHEMBL28339029 0.87 DRD2 (0.52) ADRA2ADRD3TSHRLMNADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504547-A Amisulpride preparation method of the composition 山东安弘制药有限公司 2025-02-25 — — CN claimed
US-20240279171-A1 METHODS FOR PREPARING CRYSTALLINE FORMS OF AMISULPRIDE SUNOVION PHARMACEUTICALS INC (US) 2024-08-22 — — US claimed
CN-117185969-A Preparation method of 4-amino-5-ethylsulfonyl-2-methoxybenzoic acid 江苏阿尔法药业股份有限公司 2023-12-08 — — CN claimed
CN-116003304-A Synthesis method of amisulpride 浙江皓华制药有限公司 2023-04-25 — — CN claimed
WO-2022256482-A1 METHODS FOR PREPARING CRYSTALLINE FORMS OF AMISULPRIDE SUNOVION PHARMACEUTICALS INC. (US) 2022-12-08 — — WO claimed
CN-113061108-A Synthesis method of amisulpride process impurities 北京万全德众医药生物技术有限公司 2021-07-02 — — CN claimed
CN-102838520-A Amisulpride preparation method BEIJING DVENTUREPHARM TECHNOLOGY DEV CO LTD 2012-12-26 — — CN claimed
CN-119504547-A Amisulpride preparation method of the composition 山东安弘制药有限公司 2025-02-25 — — CN disclosed
CN-119504547-A Amisulpride preparation method of the composition 山东安弘制药有限公司 2025-02-25 — — CN disclosed
CN-118993969-B Industrial production method for amisulpride 广州市桐晖药业有限公司 2025-01-24 — — CN disclosed
US-12161623-B2 Nonracemic mixtures and uses thereof SUNOVION PHARMACEUTICALS INC. (US) 2024-12-10 — — US disclosed
US-12161758-B2 Modified release formulations and uses thereof SUNOVION PHARMACEUTICALS INC. (US) 2024-12-10 — — US disclosed
CN-118993969-A Industrial production method for amisulpride 广州市桐晖药业有限公司 2024-11-22 — — CN disclosed
US-4816471-A NERVOUS SYSTEM DISORDERS SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILLE-DE FRANCE (FR) 1989-03-28 — — US disclosed
US-4673686-A CNS MODIFIERS, ANTI-APOMORPHINE ANTIENETIC ACITIVTY/ SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLE DE L'ILE DE FRANCE (FR) 1987-06-16 — — US disclosed
EP-0055524-B1 BICYCLO (3,2,1) OCTYLBENZAMIDES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BEECHAM GROUP PLC (GB) 1984-10-17 — — EP disclosed
US-4410535-A ANTIEMETICS BEECHAM GROUP LIMITED (GB) 1983-10-18 — — US disclosed
US-4401822-A ANISEROTONINE AGENTS; APOMORPHINE ANTAGONIST SOCIETE DE'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE FRANCE (FR) 1983-08-30 — — US disclosed
EP-0055524-A2 Bicyclo (3,2,1) octylbenzamides, a process for their preparation and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1982-07-07 — — EP disclosed
US-4294828-A ANTIEMETIC AND ANTISEROTONIN SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE-FRANCE (FR) 1981-10-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12161623-B2 Nonracemic mixtures and uses thereof TPMT, AASDHPPT, SIGMAR1 ADRA2A 111/4885DRD3 1446/4885TSHR 2384/4885
US-12161758-B2 Modified release formulations and uses thereof SRI, ABCG2, SUCNR1 ADRA2A 44/4885DRD3 1089/4885TSHR 1193/4885
US-20240279171-A1 METHODS FOR PREPARING CRYSTALLINE FORMS OF AMISULPRIDE U2SURP, HMGCR, ABCG2 ADRA2A 246/4885DRD3 875/4885TSHR 1081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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