SCHEMBL10725552

SCHEMBL10725552

CCOC(=O)CCc1cccc(CO)c1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 4/20 0.61
CYP4A11 Q02928 4/20 0.61
TDP1 Q9NUW8 2/20 0.50
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
CYP4Z1 Q86W10 1/20 0.46
SYK P43405 2/20 0.45
ALOX5 P09917 1/20 0.45
ALDH1A1 P00352 1/20 0.45
GAA P10253 1/20 0.45
APP P05067 1/20 0.44
PDE3B Q13370 1/20 0.44
PDE3A Q14432 1/20 0.44
P2RY12 Q9H244 1/20 0.44
ABCB1 P08183 1/20 0.44
RAB9A P51151 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4425984 0.93 CYP4F2 (0.64) CYP4F2CYP4A11TDP1PPARGPPARA
SCHEMBL22070553 0.90 CYP4F2 (0.76) CYP4F2CYP4A11TDP1PPARGPPARA
SCHEMBL19089798 0.89 CYP4F2 (0.61) CYP4F2CYP4A11PPARGPPARACYP4Z1
SCHEMBL13104077 0.89 CYP4F2 (0.58) CYP4F2CYP4A11TDP1PPARGPPARA
SCHEMBL3175607 0.88 CYP4F2 (0.65) CYP4F2CYP4A11TDP1PPARGPPARA
SCHEMBL3175580 0.87 CYP4F2 (0.57) CYP4F2CYP4A11TDP1PPARGPPARA
SCHEMBL10504954 0.86 CYP4F2 (0.55) CYP4F2CYP4A11TDP1PPARGPPARA
SCHEMBL2174850 0.86 CYP4F2 (0.55) CYP4F2CYP4A11TDP1PPARGPPARA
SCHEMBL879289 0.85 CYP4F2 (0.58) CYP4F2CYP4A11TDP1PPARGPPARA
Hydrochloric Acid SCHEMBL6982286 0.84 CYP4F2 (0.54) CYP4F2CYP4A11TDP1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11365192-B2 Pyridine compound substituted with azole TAISHO PHARMACEUTICAL CO., LTD. (JP) 2022-06-21 US disclosed
US-20210122741-A1 PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE TAISHO PHARMACEUTICAL CO., LTD (JP) 2021-04-29 US disclosed
EP-3666766-A1 PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE Taisho Pharmaceutical Co., Ltd. (JP) 2020-06-17 EP disclosed
CN-110914254-A Azole-substituted pyridine compound 大正制药株式会社 2020-03-24 CN disclosed
US-4668698-A [(4-phenyl-1,3-dioxan-cis-5-yl)alkyl]phenylalkanoic acid derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-05-26 US disclosed
EP-0142324-A2 Phenylalkanoic acid derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210122741-A1 PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE CYP2C19, CYP4A11, CYP11B1 CYP4F2 20/4885CYP4A11 2/4885TDP1 4253/4885
US-11365192-B2 Pyridine compound substituted with azole CYP2C19, CYP4A11, CYP11B1 CYP4F2 20/4885CYP4A11 2/4885TDP1 4253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.