Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.64 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 2/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13104077 | 0.95 | CYP4F2 (0.58) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL3175580 | 0.93 | CYP4F2 (0.57) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL10725552 | 0.93 | CYP4F2 (0.61) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL22070553 | 0.93 | CYP4F2 (0.76) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL2174850 | 0.92 | CYP4F2 (0.55) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL10504954 | 0.92 | CYP4F2 (0.55) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL879289 | 0.91 | CYP4F2 (0.58) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL3175607 | 0.91 | CYP4F2 (0.65) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| Hydrochloric Acid SCHEMBL6982286 | 0.91 | CYP4F2 (0.54) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL2745464 | 0.90 | CYP4F2 (0.57) | CYP4F2CYP4A11TDP1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479203-A1 | AROMATIC POLYESTER | Muroran Institute of Technology (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20120172570-A1 | AROMATIC POLYESTER | NITTA CORPORATION | 2012-07-05 | — | — | US | disclosed |
| US-7557126-B2 | Diphenylmethyl compounds useful as muscarinic receptor antagonists | THERAVANCE, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-20070254943-A1 | Diphenylmethyl compounds useful as muscarinic receptor antagonists | THERAVANCE BIOPHARMA R&D IP, LLC | 2007-11-01 | — | — | US | disclosed |
| US-7250414-B2 | Diphenylmethyl compounds useful as muscarinic receptor antagonists | THERAVANCE, INC. (US) | 2007-07-31 | — | — | US | disclosed |
| EP-1723142-A1 | DIPHENYLMETHYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | Theravance, Inc. (US) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005087763-A9 | DIPHENYLMETHYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE INC (US) | 2005-10-27 | — | — | WO | disclosed |
| WO-2005087763-A1 | DIPHENYLMETHYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050203167-A1 | Diphenylmethyl compounds useful as muscarinic receptor antagonists | THERAVANCE, INC. | 2005-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203167-A1 | Diphenylmethyl compounds useful as muscarinic receptor antagonists | CHRM1, CHRM2, CHRM3 | CYP4F2 1689/4885CYP4A11 935/4885TDP1 3041/4885 |
| US-20070254943-A1 | Diphenylmethyl compounds useful as muscarinic receptor antagonists | CHRM1, CHRM2, CHRM3 | CYP4F2 1689/4885CYP4A11 935/4885TDP1 3041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.