Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.58 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425984 | 0.95 | CYP4F2 (0.64) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL19089791 | 0.90 | ALOX5 (0.57) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL3175580 | 0.89 | CYP4F2 (0.57) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL22070553 | 0.89 | CYP4F2 (0.76) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL10725552 | 0.89 | CYP4F2 (0.61) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL10504954 | 0.87 | CYP4F2 (0.55) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL2174850 | 0.87 | CYP4F2 (0.55) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL879289 | 0.87 | CYP4F2 (0.58) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| Hydrochloric Acid SCHEMBL6982286 | 0.86 | CYP4F2 (0.54) | CYP4F2CYP4A11TDP1PPARGPPARA | |
| SCHEMBL3175607 | 0.86 | CYP4F2 (0.65) | CYP4F2CYP4A11TDP1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397614-B1 | IONIZABLE CATIONIC LIPID | ARCTURUS THERAPEUTICS INC (US) | 2022-05-18 | — | — | EP | disclosed |
| US-8304403-B2 | Heterocyclic CETP inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-11-06 | — | — | US | disclosed |
| US-20100267669-A1 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267669-A1 | HETEROCYCLIC CETP INHIBITORS | CETP, CES1, NPC1 | CYP4F2 1512/4885CYP4A11 357/4885TDP1 610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.