Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.69 |
| ▸ | TOP1 | P11387 | 4/20 | 0.51 |
| ▸ | CYCS | P99999 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794157 | 0.91 | TOP1 (0.61) | ENPP2TOP1CYCSMEN1KMT2A | |
| SCHEMBL29558419 | 0.91 | TOP1 (0.61) | ENPP2TOP1CYCSMEN1KMT2A | |
| SCHEMBL10730297 | 0.87 | MEN1 (0.57) | ENPP2TOP1CYCSMEN1KMT2A | |
| SCHEMBL218702 | 0.84 | ENPP2 (0.97) | ENPP2TOP1CYCSABCG2TERT | |
| SCHEMBL29368142 | 0.84 | ENPP2 (0.97) | ENPP2TOP1CYCSABCG2TERT | |
| Water SCHEMBL23522817 | 0.83 | ENPP2 (0.94) | ENPP2TOP1CYCSABCG2TERT | |
| Ammonia Solution, Strong SCHEMBL3001889 | 0.83 | ENPP2 (0.94) | ENPP2TOP1CYCSABCG2TERT | |
| Tetraphenylporphine Tetrasulfonic Acid SCHEMBL20456165 | 0.83 | ENPP2 (1.00) | ENPP2TOP1CYCSABCG2TERT | |
| SCHEMBL17768419 | 0.83 | ENPP2 (0.94) | ENPP2TOP1CYCSABCG2TERT | |
| SCHEMBL16336184 | 0.83 | ENPP2 (0.94) | ENPP2TOP1CYCSABCG2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127797-B1 | LABELLED MOLECULES FOR FLUORESCENCE IMMUNOASSAYS AND PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-06-16 | — | — | EP | claimed |
| US-4614723-A | Porphyrin derivatives as fluorescent markers for immunoassays | HOFFMANN-LA ROCHE INC. (US) | 1986-09-30 | — | — | US | claimed |
| EP-0127797-A1 | Labelled molecules for fluorescence immunoassays and processes and intermediates for their preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-12-12 | — | — | EP | claimed |
| EP-0127797-B1 | LABELLED MOLECULES FOR FLUORESCENCE IMMUNOASSAYS AND PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-06-16 | — | — | EP | disclosed |
| US-4614723-A | Porphyrin derivatives as fluorescent markers for immunoassays | HOFFMANN-LA ROCHE INC. (US) | 1986-09-30 | — | — | US | disclosed |
| EP-0127797-A1 | Labelled molecules for fluorescence immunoassays and processes and intermediates for their preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-12-12 | — | — | EP | disclosed |