Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.86 |
| ▸ | MEN1 | O00255 | 2/20 | 0.86 |
| ▸ | MMP2 | P08253 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GPR183 | P32249 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | GBA1 | P04062 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15010078 | 0.93 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1MMP2KDM4E | |
| SCHEMBL31684032 | 0.91 | ALDH1A1 (0.97) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL4555970 | 0.91 | ALDH1A1 (0.97) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL27974975 | 0.90 | ALDH1A1 (0.76) | ALDH1A1KMT2AMEN1MMP2KDM4E | |
| SCHEMBL848429 | 0.88 | KMT2A (0.73) | ALDH1A1KMT2AMEN1MMP2KDM4E | |
| SCHEMBL654409 | 0.88 | MEN1 (0.73) | ALDH1A1KMT2AMEN1MMP2HTT | |
| SCHEMBL2960456 | 0.87 | MEN1 (0.68) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL2933909 | 0.87 | KMT2A (0.68) | ALDH1A1KMT2AMEN1MMP2KDM4E | |
| SCHEMBL18711336 | 0.86 | MEN1 (0.69) | ALDH1A1KMT2AMEN1GPR183 | |
| SCHEMBL5245856 | 0.84 | MEN1 (0.62) | ALDH1A1KMT2AMEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663641-A | LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES | RICOH COMPANY, LTD. (JP) | 1987-05-05 | — | — | US | disclosed |