Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292855 | 0.81 | KDM4E (0.53) | KDM4EGPR3CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8574548 | 0.78 | KDM4E (0.56) | KDM4EGPR3CYP1A2CYP3A4ALDH1A1 | |
| Bromide SCHEMBL5777889 | 0.77 | KDM4E (0.55) | KDM4EGPR3CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL13696902 | 0.76 | ALDH1A1 (0.49) | KDM4ECYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL5363783 | 0.74 | DAO (0.51) | KDM4ECYP1A2CYP3A4ALDH1A1MAPT | |
| SCHEMBL861279 | 0.74 | KDM4E (0.51) | KDM4EGPR3CYP1A2CYP3A4MAPT | |
| SCHEMBL5236795 | 0.73 | CYP1A2 (0.68) | KDM4ECYP1A2CYP2C19CYP3A4HIF1A | |
| Phenanthridine SCHEMBL11355234 | 0.73 | KDM4E (0.74) | KDM4EGPR3CYP3A4ALDH1A1MAPT | |
| SCHEMBL27908893 | 0.72 | KDM4E (0.56) | KDM4EGPR3CYP3A4ALDH1A1MAPT | |
| SCHEMBL9053551 | 0.71 | KDM4E (0.55) | KDM4EGPR3ALDH1A1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4689326-A | DIBENZOHOMOPIPERIDINE OR AMIDE OR IMIDE ANALOG | RESEARCH CORPORATION (US) | 1987-08-25 | — | — | US | disclosed |