Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30244780 | 0.86 | DAO (0.52) | DAONPC1MAPTRAB9ACYP1A2 | |
| SCHEMBL3584548 | 0.86 | DAO (0.52) | DAONPC1MAPTRAB9ACYP1A2 | |
| SCHEMBL28759783 | 0.85 | DAO (0.54) | DAONPC1MAPTRAB9AKDM4E | |
| SCHEMBL19141142 | 0.85 | DAO (0.51) | DAONPC1MAPTRAB9AKDM4E | |
| SCHEMBL24814483 | 0.84 | HDAC3 (0.58) | DAONPC1MAPTRAB9AKDM4E | |
| SCHEMBL22919854 | 0.84 | ALOX15 (0.56) | DAONPC1MAPTRAB9AHDAC3 | |
| SCHEMBL3589062 | 0.82 | PDE3B (0.55) | DAOMAPTKDM4ETP53HDAC3 | |
| Benzylacetone SCHEMBL28262024 | 0.82 | ALDH1A1 (0.64) | NPC1MAPTRAB9AKDM4ELMNA | |
| SCHEMBL12251083 | 0.81 | ANO1 (0.57) | DAONPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28765952 | 0.81 | IAPP (0.50) | DAOLMNACYP1A2CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2750504-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC Therapeutics, Inc. (US) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013033258-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS, INC. (US) | 2013-03-07 | — | — | WO | disclosed |
| WO-2007144376-A2 | LIGHTENING AND/OR DYEING AGENTS WITH ESTERS AND/OR ANHYDRIDES | HENKEL AG & CO. KGAA (DE) | 2007-12-21 | — | — | WO | disclosed |
| EP-0124992-A1 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1984-11-14 | — | — | EP | disclosed |