Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10728297 | 0.98 | MAPT (0.37) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL10727475 | 0.97 | MAPT (0.38) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL10732645 | 0.94 | MAPT (0.39) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL10732803 | 0.77 | MAPT (0.37) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL7934805 | 0.76 | MAPT (0.52) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL10734145 | 0.71 | MAPT (0.45) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL7925548 | 0.71 | CES2 (0.42) | MAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL8995854 | 0.71 | MAPT (0.40) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL7971082 | 0.69 | CYP2C19 (0.33) | ALDH1A1KDM4ETSHR | |
| SCHEMBL10191378 | 0.69 | ALDH1A1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4693745-A | Cyclohexanedionecarboxylic acid derivatives with herbicidal and plant growth regulating properties | CIBA-GEIGY CORPORATION (US) | 1987-09-15 | — | — | US | claimed |
| US-4693745-A | Cyclohexanedionecarboxylic acid derivatives with herbicidal and plant growth regulating properties | CIBA-GEIGY CORPORATION (US) | 1987-09-15 | — | — | US | disclosed |