Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.70 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.69 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | MAOA | P21397 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 1/20 | 0.67 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.63 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.62 |
| ▸ | FBP1 | P09467 | 2/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SNCA | P37840 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10728549 | 1.00 | APP (0.70) | APPPTGS2PTGS1MAOAMAOB | |
| SCHEMBL1005734 | 0.93 | PTGS2 (0.78) | APPPTGS2PTGS1MAOAMAOB | |
| SCHEMBL1005735 | 0.93 | PTGS2 (0.78) | APPPTGS2PTGS1MAOAMAOB | |
| SCHEMBL9589678 | 0.87 | MAOB (0.64) | APPPTGS2PTGS1MAOAMAOB | |
| SCHEMBL9589680 | 0.87 | MAOB (0.64) | APPPTGS2PTGS1MAOAMAOB | |
| SCHEMBL14880486 | 0.86 | PTGS2 (0.63) | APPPTGS2PTGS1MAOAMAOB | |
| SCHEMBL8721746 | 0.85 | MAOB (0.66) | APPPTGS2PTGS1MAOAMAOB | |
| SCHEMBL8721744 | 0.85 | MAOB (0.66) | APPPTGS2PTGS1MAOAMAOB | |
| SCHEMBL7622323 | 0.85 | APP (0.95) | APPPTGS2PTGS1MAOBFBP1 | |
| SCHEMBL11121103 | 0.85 | APP (0.95) | APPPTGS2PTGS1MAOBFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62136601-A | — | — | None | — | — | JP | disclosed |
| JP-S62136601-A | ORGANIC NONLINEAR OPTICAL MATERIAL | NIPPON TELEGR & TELEPH CORP <NTT> | 1987-06-19 | — | — | JP | disclosed |