Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.58 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.57 |
| ▸ | FBP1 | P09467 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1005735 | 0.89 | PTGS2 (0.78) | PTGS2PTGS1MAOAMAOBAPP | |
| SCHEMBL1005734 | 0.89 | PTGS2 (0.78) | PTGS2PTGS1MAOAMAOBAPP | |
| SCHEMBL492221 | 0.88 | APP (0.70) | PTGS2PTGS1MAOAMAOBAPP | |
| SCHEMBL20328414 | 0.88 | APP (0.70) | PTGS2PTGS1MAOAMAOBAPP | |
| SCHEMBL20328415 | 0.88 | APP (0.70) | PTGS2PTGS1MAOAMAOBAPP | |
| SCHEMBL8039805 | 0.88 | RAB9A (0.59) | PTGS2PTGS1MAOAMAOBAPP | |
| SCHEMBL31096483 | 0.86 | APP (0.68) | PTGS2PTGS1MAOAMAOBAPP | |
| Hydrochloric Acid SCHEMBL15269629 | 0.86 | APP (0.68) | PTGS2PTGS1MAOAMAOBAPP | |
| SCHEMBL28853641 | 0.86 | APP (0.68) | PTGS2PTGS1MAOAMAOBAPP | |
| Ethane SCHEMBL10589507 | 0.86 | APP (0.68) | PTGS2PTGS1MAOAMAOBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780326-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | Vivolux Ab (SE) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013058691-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | VIVOLUX AB (SE) | 2013-04-25 | — | — | WO | disclosed |