SCHEMBL10728699

SCHEMBL10728699

C=CC[S+]([O-])C/C=C\SSC/C=C/C

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10728708 1.00 PTGS2 (0.34) PTGS2
SCHEMBL10728691 1.00 PTGS2 (0.34) PTGS2
Ajoene SCHEMBL3341700 0.86 PTGS2 (0.46) PTGS2
Ajoene SCHEMBL3341704 0.86 PTGS2 (0.46) PTGS2
(Z)-Ajoene SCHEMBL3305767 0.86 PTGS2 (0.46) PTGS2
Ajoene SCHEMBL465526 0.86 PTGS2 (0.46) PTGS2
Ajoene SCHEMBL1843901 0.86 PTGS2 (0.46) PTGS2
SCHEMBL10724366 0.84 PTGS2 (0.33) PTGS2
SCHEMBL10723552 0.81 PTGS2 (0.30) PTGS2
SCHEMBL10723564 0.81 PTGS2 (0.30) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4643994-A ANTICOAGULANTS, ANTIBIOTICS THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1987-02-17 US disclosed
EP-0185324-A2 Novel organic trithio oxides and method for the preparation thereof THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1986-06-25 EP disclosed