Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ajoene SCHEMBL3341704 | 1.00 | PTGS2 (0.46) | PTGS2TRPA1ALDH1A1CYP3A4HPGD | |
| Ajoene SCHEMBL465526 | 1.00 | PTGS2 (0.46) | PTGS2TRPA1ALDH1A1CYP3A4HPGD | |
| Ajoene SCHEMBL1843901 | 1.00 | PTGS2 (0.46) | PTGS2TRPA1ALDH1A1CYP3A4HPGD | |
| Ajoene SCHEMBL3341700 | 1.00 | PTGS2 (0.46) | PTGS2TRPA1ALDH1A1CYP3A4HPGD | |
| Ajoene SCHEMBL17873665 | 0.90 | PTGS2 (0.39) | PTGS2TRPA1ALDH1A1CYP3A4HPGD | |
| Ajoene SCHEMBL28098809 | 0.90 | PTGS2 (0.39) | PTGS2TRPA1ALDH1A1CYP3A4HPGD | |
| Ajoene SCHEMBL17785554 | 0.90 | PTGS2 (0.42) | PTGS2TRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL10728699 | 0.86 | PTGS2 (0.34) | PTGS2 | |
| SCHEMBL10728691 | 0.86 | PTGS2 (0.34) | PTGS2 | |
| SCHEMBL10728708 | 0.86 | PTGS2 (0.34) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709166-A1 | NOVEL INSECTICIDAL MIXTURES FOR CONTROLLING AND PROTECTING CROPS | ADAMA MAKHTESHIM LTD. (IL) | 2026-03-18 | — | — | EP | claimed |
| EP-4637733-A1 | TREATMENT OF MYELOPEROXIDASE-POSITIVE ANCA-ASSOCIATED VASCULITIS WITH H2S RELEASING COMPOUNDS | Debreceni Egyetem (HU) | 2025-10-29 | — | — | EP | claimed |
| EP-4615506-A1 | USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES | Sahin, Fikret (TR) | 2025-09-17 | — | — | EP | claimed |
| WO-2024258363-A1 | USE OF GSK-3 ACTIVATIOR TO MODULATE PROTEASOME ACTIVITY TO PREVENT AGEING ASSOCIATED CONDITIONS AND DISEASES | SAHIN FIKRET (TR) | 2024-12-19 | — | — | WO | claimed |
| WO-2024231927-A1 | NOVEL INSECTICIDAL MIXTURES FOR CONTROLLING AND PROTECTING CROPS | ADAMA MAKHTESHIM LTD. (IL) | 2024-11-14 | — | — | WO | claimed |
| WO-2024134235-A1 | TREATMENT OF MYELOPEROXIDASE-POSITIVE ANCA-ASSOCIATED VASCULITIS WITH H2S RELEASING COMPOUNDS | DEBRECENI EGYETEM (HU) | 2024-06-27 | — | — | WO | claimed |
| CN-103328441-A | Process for the manufacture of ajoene derivatives | UNIV DENMARK TECH DTU | 2013-09-25 | — | — | CN | claimed |
| EP-2110128-A1 | USE OF PARTICULAR ANTIBACTERIAL COMPOUNDS, WHICH ARE DERIVED FROM ALLIACEAE, AS NATURAL ADDITIVES IN ANIMAL FEED | DMC Research Center, S.L. (ES) | 2009-10-21 | — | — | EP | claimed |
| US-7321002-B2 | Chiral integrin modulators and methods of use thereof | BILLINGS PHARMACEUTICALS, INC. (US) | 2008-01-22 | — | — | US | claimed |
| US-20060205824-A1 | Chiral integrin modulators and methods of use thereof | BILLINGS PHARMACEUTICALS, INC. | 2006-09-14 | — | — | US | claimed |
| US-7045663-B2 | Chiral integrin modulators and methods of use thereof | BILLINGS PHARMACEUTICALS, INC. (US) | 2006-05-16 | — | — | US | claimed |
| EP-1309548-A4 | CHIRAL INTEGRIN MODULATORS AND METHODS OF USE THEREOF | BILLINGS PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | EP | claimed |
| WO-2002004413-A9 | CHIRAL INTEGRIN MODULATORS AND METHODS OF USE THEREOF | DAVIDSON JOHN B (US) | 2004-05-06 | — | — | WO | claimed |
| US-20040053892-A1 | Chiral integrin modulators and methods of use thereof | BILLINGS PHARMACEUTICALS, INC. | 2004-03-18 | — | — | US | claimed |
| EP-1309548-A1 | CHIRAL INTEGRIN MODULATORS AND METHODS OF USE THEREOF | Billings Pharmaceuticals, Inc. (US) | 2003-05-14 | — | — | EP | claimed |
| WO-2002004413-A1 | CHIRAL INTEGRIN MODULATORS AND METHODS OF USE THEREOF | DAVIDSON JOHN B (US) | 2002-01-17 | — | — | WO | claimed |
| JP-8012570-A | — | — | None | — | — | JP | disclosed |
| EP-4709166-A1 | NOVEL INSECTICIDAL MIXTURES FOR CONTROLLING AND PROTECTING CROPS | ADAMA MAKHTESHIM LTD. (IL) | 2026-03-18 | — | — | EP | disclosed |
| US-4643994-A | ANTICOAGULANTS, ANTIBIOTICS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1987-02-17 | — | — | US | disclosed |
| EP-0185324-A2 | Novel organic trithio oxides and method for the preparation thereof | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1986-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205824-A1 | Chiral integrin modulators and methods of use thereof | ITGB1, ITGB5, ITGB3 | PTGS2 2962/4885TRPA1 1023/4885ALDH1A1 289/4885 |
| US-20040053892-A1 | Chiral integrin modulators and methods of use thereof | ITGB1, ITGA1, ITGAM | PTGS2 2449/4885TRPA1 1231/4885ALDH1A1 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.