Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697250 | 1.00 | THRA (0.65) | THRATHRBPLA2G4BESR1PRSS1 | |
| SCHEMBL2313353 | 0.89 | THRA (0.67) | THRATHRBPLA2G4BESR1PRSS1 | |
| SCHEMBL27804692 | 0.88 | KMT2A (0.55) | THRATHRBPLA2G4BPRSS1MAPT | |
| SCHEMBL6259180 | 0.88 | PRSS1 (0.56) | THRATHRBPLA2G4BPRSS1MAPT | |
| SCHEMBL28748738 | 0.88 | THRA (0.65) | THRATHRBPLA2G4BESR1PRSS1 | |
| SCHEMBL12431954 | 0.87 | PLA2G4B (0.77) | THRATHRBPLA2G4BESR1PRSS1 | |
| SCHEMBL9626808 | 0.87 | PLA2G4B (0.77) | THRATHRBPLA2G4BESR1PRSS1 | |
| SCHEMBL7696499 | 0.87 | PLA2G4B (0.77) | THRATHRBPLA2G4BESR1PRSS1 | |
| SCHEMBL5913195 | 0.87 | KMT2A (0.62) | MAPTALDH1A1RAB9ANPC1PKM | |
| Hydrochloric Acid SCHEMBL6259177 | 0.87 | PRSS1 (0.57) | THRATHRBPLA2G4BPRSS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4713165-A | Sensor having ion-selective electrodes | ILEX CORPORATION (US) | 1987-12-15 | — | — | US | disclosed |
| EP-0230449-A1 | SENSOR HAVING ION-SELECTIVE ELECTRODES | EOS TECHNOLOGY CORPORATION (US) | 1987-08-05 | — | — | EP | disclosed |
| WO-1987000286-A1 | SENSOR HAVING ION-SELECTIVE ELECTRODES | ILEX CORPORATION (US) | 1987-01-15 | — | — | WO | disclosed |