Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697250 | 0.88 | THRA (0.65) | KMT2AALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL6259180 | 0.88 | PRSS1 (0.56) | KMT2AALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL10728889 | 0.88 | THRA (0.65) | KMT2AALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL5913195 | 0.87 | KMT2A (0.62) | KMT2AALDH1A1RAB9AMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL6259177 | 0.87 | PRSS1 (0.57) | KMT2AALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL566268 | 0.82 | THRA (0.55) | KMT2AALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL28483458 | 0.82 | ALDH1A1 (0.63) | KMT2AALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL10915750 | 0.81 | KMT2A (0.61) | KMT2AALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL28158589 | 0.80 | AKR1C3 (0.57) | KMT2AALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL10368252 | 0.80 | THRA (0.47) | KMT2AALDH1A1RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101747292-B | Benzoylguanidine-trimetazidine conjugate, as well as preparation method and medical application thereof | UNIV CHINA PHARMA | 2011-07-20 | — | — | CN | disclosed |
| CN-101747292-A | Benzoylguanidine-trimetazidine conjugate, as well as preparation method and medical application thereof | UNIV CHINA PHARMA | 2010-06-23 | — | — | CN | disclosed |