Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30575164 | 1.00 | TDP1 (0.50) | TDP1HPGDGPR35ALDH1A1KDM4E | |
| Ammonia Solution, Strong SCHEMBL28217172 | 0.98 | HPGD (0.49) | TDP1HPGDGPR35ALDH1A1KDM4E | |
| SCHEMBL3010961 | 0.84 | TDP1 (0.61) | TDP1GPR35ALDH1A1MEN1KMT2A | |
| SCHEMBL27857909 | 0.84 | ALDH1A1 (0.54) | TDP1GPR35ALDH1A1MEN1KMT2A | |
| SCHEMBL18554455 | 0.83 | HPGD (0.47) | TDP1HPGDGPR35ALDH1A1KDM4E | |
| Ammonia Solution, Strong SCHEMBL28763100 | 0.82 | TDP1 (0.58) | TDP1GPR35ALDH1A1MEN1KMT2A | |
| SCHEMBL26164137 | 0.82 | HPGD (0.46) | TDP1HPGDGPR35ALDH1A1KDM4E | |
| SCHEMBL29565619 | 0.82 | HPGD (0.46) | TDP1HPGDGPR35ALDH1A1KDM4E | |
| SCHEMBL30490230 | 0.81 | TDP1 (0.57) | TDP1HPGDALDH1A1MAPK1TSHR | |
| SCHEMBL8013048 | 0.81 | TDP1 (0.57) | TDP1HPGDALDH1A1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 618 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805080-B | Method for continuously separating 3-chloro-4-fluoronitrobenzene | 福建技术师范学院 | 2024-06-14 | — | — | CN | claimed |
| CN-117886662-A | Efficient production method of 2, 6-dichlorofluorobenzene combined with wastewater treatment | 浙江解氏新材料股份有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-115453000-B | Detection method and application of toxic impurities in tenib drug intermediate | 广州艾格生物科技有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-112010732-B | Preparation method of 3, 5-dichloro-4-fluorobromobenzene compound | 内蒙古永太化学有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-115453000-A | Detection method and application of toxic impurities in tinib drug intermediate | 广州艾格生物科技有限公司 | 2022-12-09 | — | — | CN | claimed |
| CN-114805080-A | Method for continuously separating 3-chloro-4-fluoronitrobenzene | 福建技术师范学院 | 2022-07-29 | — | — | CN | claimed |
| CN-114539080-A | Preparation method of 2- (2-amino-6-chlorphenyl) -sodium acetate | 八叶草健康产业研究院(厦门)有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-113582804-A | Production process for producing high-purity 2, 4-dichlorofluorobenzene from p-nitrochlorobenzene | 浙江省常山长盛化工有限公司 | 2021-11-02 | — | — | CN | claimed |
| CN-112010732-A | Preparation method of 3, 5-dichloro-4-fluorobromobenzene compound | 内蒙古永太化学有限公司 | 2020-12-01 | — | — | CN | claimed |
| CN-109293503-A | A kind of preparation method of the fluoro- 3- chlorobenzoic acid of 2,4,5- tri- | 浙江工业大学上虞研究院有限公司 | 2019-02-01 | — | — | CN | claimed |
| EP-0536175-B1 | PROCESS FOR PRODUCING CHLOROFLUORONITRO BENZENES AND DIFLUORONITRO BENZENES | HOECHST AG (DE) | 1995-09-20 | — | — | EP | claimed |
| EP-0539765-B1 | Process for the preparation of 2,4-dichlorofluorobenzene | HOECHST AG (DE) | 1994-07-20 | — | — | EP | claimed |
| US-5302742-A | Process for the preparation of N-acylated p-amino-phenols | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-12 | — | — | US | claimed |
| EP-0569792-A2 | Process for the preparation of N-acylated p-aminophenols | BAYER AG (DE) | 1993-11-18 | — | — | EP | claimed |
| US-5227545-A | PROCESS FOR THE PREPARATION OF 2,4-DICHLOROFLUOROBENZENE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-13 | — | — | US | claimed |
| US-5126485-A | Inhibition of dehalogenation during catalytic hydrogenation | RHONE-POULENC CHIMIE (FR) | 1992-06-30 | — | — | US | claimed |
| CN-1013108-B | PRODN. PROCESS FOR CHLOROFLUORONITROBENZENE | RES INST OF APPLIED CHEMISTRY (CN) | 1991-07-10 | — | — | CN | claimed |
| CN-1033272-A | The production method of chloro fluoro nitrobenzene | RES INST OF APPLIED CHEMISTRY (CN) | 1989-06-07 | — | — | CN | claimed |
| US-4642399-A | REACTION OF CHLORONITRO BENZENE COMPOUNDS WITH FLUORIDE SALT | MALLINCKRODT, INC. (US) | 1987-02-10 | — | — | US | claimed |
| US-4418229-A | DISPLACEMENT OF CHLORONITROBENZENES WITH A FLUORIDE SALT, QUATERNARY AMMONIUM PHASE TRANSFER CATALYSTS | MALLINCKRODT, INC. (US) | 1983-11-29 | — | — | US | claimed |