Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28217172

N.O=[N+]([O-])c1cccc(Cl)c1F

nearest known ligand 0.49

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.49
TDP1 Q9NUW8 4/20 0.48
GPR35 Q9HC97 2/20 0.47
ALDH1A1 P00352 4/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MAPK1 P28482 3/20 0.43
MAPT P10636 2/20 0.43
POLB P06746 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
TSHR P16473 4/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MAPK13 O15264 1/20 0.41
MAPK12 P53778 1/20 0.41
MAPK11 Q15759 1/20 0.41
MAPK14 Q16539 1/20 0.41
S100A4 P26447 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL107291 0.98 TDP1 (0.50) HPGDTDP1GPR35ALDH1A1MEN1
SCHEMBL30575164 0.98 TDP1 (0.50) HPGDTDP1GPR35ALDH1A1MEN1
Ammonia Solution, Strong SCHEMBL28763100 0.85 TDP1 (0.58) TDP1GPR35ALDH1A1MEN1KMT2A
SCHEMBL3010961 0.83 TDP1 (0.61) TDP1GPR35ALDH1A1MEN1KMT2A
SCHEMBL27857909 0.82 ALDH1A1 (0.54) TDP1GPR35ALDH1A1MEN1KMT2A
SCHEMBL18554455 0.82 HPGD (0.47) HPGDTDP1GPR35ALDH1A1MEN1
SCHEMBL26164137 0.80 HPGD (0.46) HPGDTDP1GPR35ALDH1A1MEN1
SCHEMBL29565619 0.80 HPGD (0.46) HPGDTDP1GPR35ALDH1A1MEN1
SCHEMBL8013048 0.79 TDP1 (0.57) HPGDTDP1ALDH1A1MAPK1TSHR
SCHEMBL30490230 0.79 TDP1 (0.57) HPGDTDP1ALDH1A1MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106117067-B A kind of method that diazotising prepares 3,5 difluoro, 4 chloronitrobenzene 江苏扬农化工集团有限公司 2018-04-20 CN disclosed