Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.65 |
| ▸ | TOP1 | P11387 | 4/20 | 0.48 |
| ▸ | CYCS | P99999 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 4/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10895316 | 1.00 | ENPP2 (0.65) | ENPP2TOP1CYCSMAPTRXFP1 | |
| SCHEMBL10895278 | 0.99 | ENPP2 (0.63) | ENPP2TOP1CYCSMAPTRXFP1 | |
| Bicarbonate SCHEMBL10724119 | 0.88 | ENPP2 (0.63) | ENPP2TOP1CYCSMAPTTERT | |
| SCHEMBL10897459 | 0.88 | TOP1 (0.53) | ENPP2TOP1CYCSMAPTRXFP1 | |
| SCHEMBL10895293 | 0.82 | ENPP2 (0.51) | ENPP2TOP1CYCSTERTABCG2 | |
| SCHEMBL218702 | 0.81 | ENPP2 (0.97) | ENPP2TOP1CYCSTERTABCG2 | |
| SCHEMBL29368142 | 0.81 | ENPP2 (0.97) | ENPP2TOP1CYCSTERTABCG2 | |
| Water SCHEMBL23522817 | 0.80 | ENPP2 (0.94) | ENPP2TOP1CYCSTERTABCG2 | |
| SCHEMBL17768419 | 0.80 | ENPP2 (0.94) | ENPP2TOP1CYCSTERTABCG2 | |
| SCHEMBL15004676 | 0.80 | ENPP2 (0.94) | ENPP2TOP1CYCSTERTABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127797-B1 | LABELLED MOLECULES FOR FLUORESCENCE IMMUNOASSAYS AND PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-06-16 | — | — | EP | claimed |
| US-4614723-A | Porphyrin derivatives as fluorescent markers for immunoassays | HOFFMANN-LA ROCHE INC. (US) | 1986-09-30 | — | — | US | claimed |
| EP-0127797-A1 | Labelled molecules for fluorescence immunoassays and processes and intermediates for their preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-12-12 | — | — | EP | claimed |
| US-4614723-A | Porphyrin derivatives as fluorescent markers for immunoassays | HOFFMANN-LA ROCHE INC. (US) | 1986-09-30 | — | — | US | disclosed |
| EP-0127797-A1 | Labelled molecules for fluorescence immunoassays and processes and intermediates for their preparation | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-12-12 | — | — | EP | disclosed |