Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.53 |
| ▸ | CYCS | P99999 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10729258 | 0.88 | ENPP2 (0.65) | TOP1CYCSMAPTRXFP1S1PR1 | |
| SCHEMBL10895316 | 0.88 | ENPP2 (0.65) | TOP1CYCSMAPTRXFP1S1PR1 | |
| SCHEMBL10895278 | 0.87 | ENPP2 (0.63) | TOP1CYCSMAPTRXFP1S1PR1 | |
| SCHEMBL17906174 | 0.81 | TOP1 (0.49) | TOP1CYCSENPP2ABCG2 | |
| SCHEMBL17906202 | 0.80 | CYCS (0.49) | TOP1CYCSENPP2ABCG2 | |
| SCHEMBL9018611 | 0.80 | TOP1 (0.52) | TOP1CYCSENPP2FFAR1SMN1; SMN2 | |
| SCHEMBL14629719 | 0.78 | TOP1 (0.41) | TOP1CYCSHDAC2HDAC1FFAR1 | |
| SCHEMBL3474355 | 0.78 | TERT (0.51) | TOP1CYCSMAPTENPP2SLC6A3 | |
| SCHEMBL10717959 | 0.78 | TERT (0.51) | TOP1CYCSMAPTENPP2SLC6A3 | |
| SCHEMBL7664820 | 0.78 | TOP1 (0.66) | TOP1CYCSMAPTENPP2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4614723-A | Porphyrin derivatives as fluorescent markers for immunoassays | HOFFMANN-LA ROCHE INC. (US) | 1986-09-30 | — | — | US | disclosed |