Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL545571 | 1.00 | TSHR (0.53) | TSHRNAPRTTDP1MEN1KMT2A | |
| Pyridine SCHEMBL3844909 | 0.97 | TSHR (0.50) | TSHRNAPRTTDP1MEN1KMT2A | |
| Pyridine SCHEMBL1097936 | 0.92 | TSHR (0.45) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL6702223 | 0.90 | TSHR (0.43) | TSHRNAPRTTDP1 | |
| Hexane SCHEMBL11381748 | 0.90 | TDP1 (0.43) | TSHRNAPRTTDP1MEN1KMT2A | |
| Pyridine SCHEMBL27766347 | 0.88 | TSHR (0.41) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL28162725 | 0.86 | TSHR (0.39) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL7121434 | 0.85 | TSHR (0.43) | TSHRNAPRTTDP1 | |
| Pyrazine SCHEMBL2492066 | 0.84 | ALDH1A1 (0.33) | KMT2A | |
| Pyridine SCHEMBL9246212 | 0.84 | LMNA (0.50) | TSHRNAPRTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4656289-A | 1,3-dibenzyl-4-halohexahydro-1H-thieno[3,4-d]imidazol-2(3H)-one intermediates | THE RESEARCH FOUNDATION OF STATE UNIV. OF NEW YORK (US) | 1987-04-07 | — | — | US | disclosed |