Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10543832 | 1.00 | CTSC (0.39) | CTSCLMNACTSSCTSKCHRM1 | |
| SCHEMBL10543826 | 1.00 | CTSC (0.39) | CTSCLMNACTSSCTSKCHRM1 | |
| SCHEMBL11369206 | 0.82 | CTSS (0.36) | CTSCLMNACTSSCTSKCHRM1 | |
| SCHEMBL10541609 | 0.81 | CAPN1 (0.47) | CTSKCTSLCTSB | |
| SCHEMBL10729925 | 0.81 | CAPN1 (0.47) | CTSKCTSLCTSB | |
| SCHEMBL8626971 | 0.81 | POLB (0.38) | CTSSCHRM1NPC1 | |
| SCHEMBL10546522 | 0.80 | GAA (0.37) | — | |
| SCHEMBL10543143 | 0.80 | GAA (0.37) | — | |
| SCHEMBL10404397 | 0.79 | GAA (0.36) | — | |
| SCHEMBL10545995 | 0.78 | GAA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4684724-A | ANTIBIOTICS, BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-08-04 | — | — | US | disclosed |
| US-4560508-A | BETA-LACTAMASE INHIBITORS, ANINICROBIAL AGENT, CHEMICAL INTERMEDIATE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-24 | — | — | US | disclosed |