Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 11/20 | 0.41 |
| ▸ | PPARG | P37231 | 11/20 | 0.41 |
| ▸ | PPARD | Q03181 | 11/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10735532 | 0.93 | HPGD (0.52) | ALDH1A1HPGDRAB9ATSHRNPC1 | |
| SCHEMBL10735929 | 0.88 | RAB9A (0.55) | ALDH1A1HPGDRAB9ATSHRNPC1 | |
| SCHEMBL10733440 | 0.88 | RAB9A (0.45) | ALDH1A1HPGDRAB9ATSHRNPC1 | |
| SCHEMBL10735435 | 0.86 | RAB9A (0.44) | ALDH1A1HPGDRAB9ATSHRNPC1 | |
| SCHEMBL10730365 | 0.86 | RAB9A (0.45) | ALDH1A1HPGDRAB9ATSHRNPC1 | |
| SCHEMBL10734835 | 0.86 | ALDH1A1 (0.42) | ALDH1A1HPGDRAB9ATSHRNPC1 | |
| SCHEMBL10728888 | 0.86 | RAB9A (0.47) | ALDH1A1HPGDRAB9ATSHRNPC1 | |
| SCHEMBL10735441 | 0.85 | RAB9A (0.46) | ALDH1A1HPGDRAB9ATSHRNPC1 | |
| SCHEMBL10733206 | 0.84 | HPGD (0.42) | ALDH1A1HPGDRAB9ATSHRNPC1 | |
| SCHEMBL10728882 | 0.84 | RAB9A (0.42) | ALDH1A1HPGDRAB9ATSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4644064-A | DIURETICS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-02-17 | — | — | US | disclosed |
| US-4504669-A | DIURETIC | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-03-12 | — | — | US | disclosed |
| US-4452804-A | DIURETICS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4427691-A | DIURETICS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1984-01-24 | — | — | US | disclosed |
| EP-0058977-A1 | 1,2-Benzisoxazoloxyethylamines, their intermediates, a process for their preparation, pharmaceutical composition containing the same and their use as diuretics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1982-09-01 | — | — | EP | disclosed |